Ionizable lipid-2 (ALC-0315 analogue) Datasheet DC Chemicals

Description	Ionizable lipid-2 is a cationic lipid for nucleic acid delivery, with the ability to form lipid nanoparticle mRNA vaccines that exhibit in vitro stability and immunostimulatory activity.This ALC-0315 analogue retains its ionizable tertiary amine, hydroxybutyl headgroup, and dual branched hydrophobic tails, while replacing the two ester linkages with carbonate groups. This modification may alter hydrolytic stability, biodegradability, membrane interactions, and overall LNP delivery performance.
Cat.No	DC60965
Name	Ionizable lipid-2 (ALC-0315 analogue)

Chemical Properties

CAS	2763904-72-7
Formula	C50H99NO7
MW	826.323577165604
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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