seMpai is a high-performance near-infrared (NIR) luciferin analogue engineered for enhanced deep-tissue bioluminescence imaging, producing a robust 675 nm emission comparable to top-tier substrates. In vitro, it effectively supports mutant luciferase systems like Akaluc, while in vivo, it enables detection of pulmonary micro-metastases, overcoming traditional D-luciferin limitations. The compound features an optimized, neutral pH formulation that reduces hepatic background, ensuring superior signal-to-noise ratios without significant toxicity, making it ideal for longitudinal studies. For optimal solubility and performance, seMpai is a critical tool for preclinical imaging and drug discovery. Learn more at MedKoo. NOTE. seMpai (Cat#465342) is the free acid form and is less water soluble. seMpai Sodium (CAT#333158) is water soluble.
