Fotemustine Datasheet DC Chemicals
Description Fotemustine is a chloroethylating nitrosourea with antineoplastic activity. Fotemustine alkylates guanine by forming chloroethyl adducts at the 6 position of guanine, resulting in N1-guanine and N3-cytosine cross linkages, inhibition of DNA synthesis, cell cycle arrest, and finally apoptosis. This agent is lipophilic and crosses the blood-brain barrier. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
Cat.No DC31115
Name Fotemustine

Chemical Properties

CAS 92118-27-9
Formula C9H19CLN3O5P
MW 315.69
Storage

References

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