NBI-74330 Datasheet DC Chemicals
Description NBI-74330 is an antagonist of CXC chemokine receptor 3 (CXCR3) with IC50 values of 7nM to18nM. NBI-74330 attenuates atherosclerotic plaque formation in LDL receptor-deficient mice. Chemokine receptor CXCR3 promotes growth of glioma. CXCR3 antagonism exerts a direct anti-glioma effect and this receptor may be a potential therapeutic target for treating human GBM.
Cat.No DC31380
Name NBI-74330

Chemical Properties

CAS 855527-92-3
Formula C32H27F4N5O3
MW 605.59
Storage

References

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