AV457 Datasheet DC Chemicals

Description	AV457 is a potent and selective mTOR inhibitor with an IC50 value of 0.54 µM. AV457 inhibits cyst growth in polycystic kidney disease (PKD) organoids. AV457 decreases the protein expression of P-s6, P-p70s6 and don’t decreases the protein expression of P-AKT.
Cat.No	DC77102
Name	AV457

Chemical Properties

CAS	2713387-11-0
Formula	C55H88N2O16S
MW	1065.36
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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