diABZI-i Datasheet DC Chemicals

Description	diABZI-i is a orthosteric STING inhibitor. diABZI-i significantly inhibits cGAMP-induced IFNβ in PBMCs with an IC50 of 49 nM. diABZI-i also activates V155M SAVI constitutive signaling in STING V155M THP-1 cells model with potent agonism (EC50: 17 nM). diABZI-i can be used for monogenic autoinflammatory disease like SAVI disease research.
Cat.No	DC78405
Name	diABZI-i

Chemical Properties

CAS
Formula	C45H50N12O6
MW	854.96
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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