DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy.
Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers.
Heparin, named after its discovery in the liver, is a mucopolysaccharide sulfate composed of glucosamine, L-idosaccharide, n-acetylglucosamine and D-glucuronic acid, with an average molecular weight of 15KDa and a strong acid. It is also found in tissues such as lungs and intestinal mucosa, and is a natural anticoagulant in animals.
Naturally occurring in mast cells, it is now mainly extracted from the mucous membrane of the bovine lung or the small intestine of pigs.
As an anticoagulant, it is a polymer formed by alternating connection of two polysaccharides, which has kang coagulation effect in vivo and in vitro, mainly used in xueshaun embolic diseases, cardiac xuguan surgery,xinzang catheterization, extracorporeal circulation, hemodialysis and so on.
With the development of pharmacology and clinical medicine, the application of heparin continues to expand.