DW34 Datasheet DC Chemicals

Description	DW34 is an orally active pan-BRD4-D1 biased inhibitor with additional BRD4-D2 inhibitive activity. DW34 displays comparable inhibitive efficacy to I-BET151 (EC50 = 0.16 μM) with low nanomolar EC50 values of 0.14 μM. DW34 significantly reduces liver inflammation induced by LPS and APAP via reducing chemokine expression and cellular necrosis.
Cat.No	DC79850
Name	DW34

Chemical Properties

CAS	2758171-54-7
Formula	C25H34N6O
MW	434.58
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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