EC-0225 Datasheet DC Chemicals
Description EC-0225, a folate conjugate of two agents- one a potent microtubule inhibiting agent, and the second a DNA alkylating agent. EC-0225 inhibits the growth of folate receptor (FR)-positive KB cells with an IC50 of ~1 nM. EC-0225 can be selectively delivered to advanced FR-positive tumors without causing overt toxicity, such as lung carcinoma.
Cat.No DC78843
Name EC-0225

Chemical Properties

CAS 926626-77-9
Formula C103H130N20O26S4
MW 2192.51
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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