GHN105 Datasheet DC Chemicals
Description GHN105 is an orally active inhibitor for STING that inhibits STING-dependent IFN-β secretion in THP-1 human monocytes with an IC50 of 4.4 μM. GHN105 reduces the IFN-β, IL-6 and CXCL10 levels in serum, and alleviates colitis in DSS.
Cat.No DC76694
Name GHN105

Chemical Properties

CAS
Formula C41H56N2O14
MW 800.89
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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