Modzatinib Datasheet DC Chemicals

Description	Modzatinib (ITK kinase-IN-1) (compound I) is an inhibitor targeting ITK kinase (IC50=8 nM, Jurkat cells) and can be used to study inflammatory diseases. Modzatinib has an IC50 of 23 nM for JAK3 in hPBMC cells (based on IL-2/pSTAT5 levels), wihout inhibitory effect against JAK2.
Cat.No	DC78635
Name	Modzatinib

Chemical Properties

CAS	2411407-25-3
Formula	C18H21F2N5O
MW	361.39
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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