Menin-MLL inhibitor MI-2 dihydrochloride Datasheet DC Chemicals

Description	Menin-MLL inhibitor MI-2 dihydrochloride is a competitive and selective Menin-MLL interaction inhibitor with an IC50 value of 446 nM and a Ki value of 158 nM. Menin-MLL inhibitor MI-2 dihydrochloride downregulates the expression of target genes such as HOXA9 and MEIS1, inhibits proliferation of leukemia cells and induces apoptosis and differentiation. Menin-MLL inhibitor MI-2 dihydrochloride is proming for rasearch of MLL-rearranged acute leukemias (e.g., AML, ALL).
Cat.No	DC78356
Name	Menin-MLL inhibitor MI-2 dihydrochloride

Chemical Properties

CAS
Formula	C18H27CL2N5S2
MW	448.48
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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