JAK2-IN-18 Datasheet DC Chemicals

Description	JAK2-IN-18 (Compound example1) is a selective JAK2 inhibitor. JAK2-IN-18 can inhibit JAK-STAT signaling and shows an IC50 of <100 nM for pSTAT5 in HEL9217 cells. JAK2-IN-18 can inhibit the proliferation of abnormally proliferating myeloid cells and can be used for the research of myeloproliferative disorders, such as essential thrombocythemia.
Cat.No	DC80879
Name	JAK2-IN-18

Chemical Properties

CAS	3104751-99-4
Formula	C40H42CLN9O3
MW	732.27
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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