Pranlukast hemihydrate Datasheet DC Chemicals

Description	Pranlukast hemihydrate (ONO-1078 hemihydrate) is an antagonist of cysteinyl leukotriene receptor-1 (CysLT1) that blocks leukotrienes such as LTC4, LTD4, and LTE4, reducing bronchoconstriction and airway inflammation. It also inhibits NF-κB activation, thereby suppressing proinflammatory cytokine production (e.g., IL-6, IL-1, TNF-α) in monocytes/macrophages and T cells, contributing to its immunomodulatory effects.
Cat.No	DC77826
Name	Pranlukast hemihydrate

Chemical Properties

CAS	150821-03-7
Formula	C27H23N5O4.1/2H2O
MW	490.51
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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