Safusidenib Datasheet DC Chemicals

Description	Safusidenib (AB-291; DS-1001) is an orally bioavailable, selective mutant IDH1 inhibitor. Safusidenib strongly inhibits mutant IDH1 but not wild-type IDH1. Safusidenib impairs tumor activity in chondrosarcoma. Safusidenib exhibits activity against IDH1R132H, and IDH1R132C with IC50s of 15, and 130 nM in assays without any preincubation, respectively.
Cat.No	DC48219
Name	Safusidenib

Chemical Properties

CAS	1898206-17-1
Formula	C25H18CL3FN2O4
MW	535.778827190399
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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