Timegadine hydrochloride Datasheet DC Chemicals
Description Timegadine hydrochloride (SR1368 hydrochloride) is the hydrochloride salt form of Timegadine. Emavusertib mesylate is an orally active inhibitor for IRAK4 (IC50=57 nM) and FLT3. Emavusertib mesylate inhibits NF-κB and MyD88 signaling pathways, reduces the generation of pro-inflammatory cytokines like IL-6 and IL-10, thereby exhibiting anti-inflammatory and anti-proliferative activities against cancer cells, leading to cell apoptosis. Emavusertib mesylate exhibits antitumor activity in mouse model.
Cat.No DC77770
Name Timegadine hydrochloride

Chemical Properties

CAS 71080-06-3
Formula C20H24CLN5S
MW 401.96
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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