AP-18 Datasheet DC Chemicals
Description AP-18, a potent and selective TRPA1 inhibitor, blocks activation of TRPA1 by 50 μM Cinnamaldehyde with an IC50 of 3.1 μM and 4.5 μM for human and mouse TRPA1, respectively. AP-18 reverses complete Freund's adjuvant (CFA)-induced mechanical hyperalgesia in mice. AP-18 attenuated 30 μM AITC-induced Yo-Pro uptake in a concentration-dependent manner, with an IC50 of 10.3 μM.
Cat.No DC42162
Name AP-18

Chemical Properties

CAS 55224-94-7
Formula C11H12CLNO
MW 209.67
Storage Please store the product under the recommended conditions in the Certificate of Analysis.

References

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