SU-909 Datasheet DC Chemicals

Description	SU-909 (SU909, IKKα-IN-48) is a potent, selective IKKα inhibitor with Ki of 0.08±0.07 uM, 10-20-fold selectivity over IKKβ (IC50=1.0±0.28 uM); inhibits FCS-stimulated phosphorylation of p100 in U2OS cells with IC50 of 8.8 uM, inhibits the noncanonical NF-kB pathway without affecting IKKβ-dependent IKappa-Bα loss in the canonical pathway.
Cat.No	DC21710
Name	SU-909

Chemical Properties

CAS	2126749-48-0
Formula	C13H10N6O2S
MW	314.322499752045
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

References 1. Anthony NG, et al. J Med Chem. 2017 Aug 24;60(16):7043-7066. View Related Products by Target IκB kinase (IKK)

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