3M-011 Datasheet DC Chemicals

Description	3M-011 is a potent TLR7/8 agonist and cytokine inducer; stimulates type I interferon (IFN) and other cytokines such as TNF-alpha, IL-12, and IFN-gamma from rat peripheral blood mononuclear cells; induces IL-12 and COX-2 expression in mDC from HIV+ and HIV- individuals, and inhibits H3N2 influenza viral replication in the nasal cavity; potentiates NK cytotoxicity, and shows antitumor effects in scid/B6 mice and scid/NOD mice.
Cat.No	DC22934
Name	3M-011

Chemical Properties

CAS	642473-62-9
Formula	C18H25N5O3S
MW	391.49
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

References 1. Martinson JA, et al. Cell Immunol. 2007 Nov-Dec;250(1-2):75-84. 2. Hammerbeck DM, et al. Antiviral Res. 2007 Jan;73(1):1-11. View Related Products by Target Toll-like Receptor (TLR)

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