CBR-5884 Datasheet DC Chemicals

Description	A potent, selective, noncompetitive inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) with IC50 of 7 uM.
Cat.No	DC23195
Name	CBR-5884

Chemical Properties

CAS	681159-27-3
Formula	C14H12N2O4S2
MW	336.386080741882
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Edouard Mullarky et al. Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancersProc Natl Acad Sci U S A, 2016 Feb 16, 113(7):1778-83.

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