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CBR-5884

  Cat. No.:  DC23195   Featured
Chemical Structure
681159-27-3
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More than 5000 active chemicals with high quality for research!
Field of application
A potent, selective, noncompetitive inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) with IC50 of 7 uM.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 681159-27-3
Chemical Name: CBR-5884
Synonyms: 5-[(2-Furanylcarbonyl)amino]-3-methyl-4-thiocyanato-2-thiophenecarboxylic acid ethyl ester;CBR 5884;CBR-5884
SMILES: CCOC(C1SC(NC(C2=CC=CO2)=O)=C(SC#N)C=1C)=O
Formula: C14H12N2O4S2
M.Wt: 336.386080741882
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: CBR-5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 33 μM.
References: [1]. Edouard Mullarky et al. Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancersProc Natl Acad Sci U S A, 2016 Feb 16, 113(7):1778-83.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
2018-0101
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