QX 314 chloride Datasheet DC Chemicals
Description A membrane-impermeable sodium channel blocker, blocks sodium current in voltage-clamped nociceptive DRG neurons.
Cat.No DC26095
Name QX 314 chloride

Chemical Properties

CAS 5369-03-9
Formula C16H27N2O+.CL-
MW 298.85138
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Rivera-Acevedo RE, et al. The quaternary lidocaine derivative, QX-314, exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels in vitro. Anesthesiology. 2011 Jun;114(6):1425-34. [2]. Talbot MJ, et al. Intracellular QX-314 inhibits calcium currents in hippocampal CA1 pyramidal neurons. J Neurophysiol. 1996 Sep;76(3):2120-4.
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