Chemical Properties
| CAS |
2104030-82-0 |
 |
| Formula |
C24H20N4O3S |
| MW |
444.505603790283 |
| Storage |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Biological activity
| Description |
CAS NO.：2104030-82-0
Product Name：6-Benzyl-3-[3-(1,3-thiazol-5-ylmethoxy)phenyl]-4,6-dihydropyrido[4,3-d]pyrimidine-2,7(1H,3H)-dione
Synonyms：Brr2 Inhibitor C9;6-Benzyl-3-(3-(thiazol-5-ylmethoxy)phenyl)-3,4-dihydropyrido[4,3-d]pyrimidine-2,7(1H,6H)-dione;6-Benzyl-3-[3-(1,3-thiazol-5-ylmethoxy)phenyl]-1,4-dihydropyrido[4,3-d]pyrimidine-2,7-dione;6-Benzyl-3-[3-(1,3-thiazol-5-ylmethoxy)phenyl]-4,6-dihydropyrido[4,3-d]pyrimidine-2,7(1H,3H)-dione
EINEC:
Molecular Formula：C24H20N4O3S
Molecular Weight：444.505603790283 |
| Target: |
IC50: 1.3 μM (Brr2)[1] |
| In Vivo |
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| In Vitro |
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| Kinase Assay |
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| Cell Assay |
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| Animal Administration |
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References
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[1]. Iwatani-Yoshihara M, et al. Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2. J Med Chem. 2017;60(13):5759-5771. |
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