KDM4D-IN-1 Datasheet DC Chemicals
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Cat.No DC10586
Name KDM4D-IN-1

Chemical Properties

CAS 2098902-68-0
Formula C11H7N5O
MW 225.2062
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：2098902-68-0
Product Name：Kdm4D-IN-1
Synonyms：KDM4D-IN-1;BCP32624;BDBM50242878;s1059
EINEC:
Molecular Formula：C11H7N5O
Molecular Weight：225.2062
Target:
In Vivo
In Vitro KDM4D-IN-1 (Compound 10r) is the most potent one with an IC50 value of 0.41±0.03 μM against KDM4D. KDM4D-IN-1 displays almost no activity against KDM2B, KDM3B, and KDM5A (IC50>10 μM), indicating that KDM4D-IN-1 has a good selectivity for KDM4D against other selected KDMs[1].
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Fang Z, et al. Discovery of pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives as a new class of histone lysine demethylase 4D (KDM4D) inhibitors. Bioorg Med Chem Lett. 2017 Jul 15;27(14):3201-3204.
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