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KDM4D-IN-1

  Cat. No.:  DC10586   Featured
Chemical Structure
2098902-68-0
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More than 5000 active chemicals with high quality for research!
Field of application
KDM4D-IN-1 is a new histone lysine demethylase 4D (KDM4D) inhibitor with an IC50 value of 0.41±0.03 μM.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2098902-68-0
Chemical Name: Kdm4D-IN-1
Synonyms: KDM4D-IN-1;BCP32624;BDBM50242878;s1059
SMILES: O=C1C2C([H])=C([H])C([H])=NC=2N2C(=C(C#N)C(C([H])([H])[H])=N2)N1[H]
Formula: C11H7N5O
M.Wt: 225.2062
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: KDM4D-IN-1 is a new histone lysine demethylase 4D (KDM4D) inhibitor with an IC50 value of 0.41±0.03 μM.
In Vitro: KDM4D-IN-1 (Compound 10r) is the most potent one with an IC50 value of 0.41±0.03 μM against KDM4D. KDM4D-IN-1 displays almost no activity against KDM2B, KDM3B, and KDM5A (IC50>10 μM), indicating that KDM4D-IN-1 has a good selectivity for KDM4D against other selected KDMs[1].
References: [1]. Fang Z, et al. Discovery of pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives as a new class of histone lysine demethylase 4D (KDM4D) inhibitors. Bioorg Med Chem Lett. 2017 Jul 15;27(14):3201-3204.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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