The animals are treated with betulonic acid amide (50 mg/kg in Tween aqueous solution) and heptral (6 mg/kg) as hepatoprotective compounds. It is found that betulonic acid amide stimulats the regenerative response in hepatocytes under conditions of combined toxic exposure and promots recovery of their qualitative and quantitative characteristics. [2]
In Vitro
BEA-NP is found over three-times more permeable than that solubilized by DMSO in Caco-2 cell monocultures.[1]
Kinase Assay
Cell Assay
Animal Administration
References
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