Cas No.: | 4481-62-3 |
Chemical Name: | Betulonicacid |
Synonyms: | Betulonic acid;Betulinonic acid;Liquidambaric acid;LiquidaMba;(+)-Betulonic Acid;3-oxolup-20(29)-en-28-oic acid;Betunolic acid;[ "3-Oxolup-20(29)-en-28-oic acid" ];Betulonicacid;BCP18477;(3As,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-9-oxo-1-prop-1-en-2-yl-2,3,4,5,6,7,7 |
SMILES: | O([H])C([C@]12C([H])([H])C([H])([H])C([H])(C(=C([H])[H])C([H])([H])[H])[C@]1([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])C(C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H])=O)=O |
Formula: | C30H46O3 |
M.Wt: | 454.6844 |
Purity: | >98%, Standard References Grade |
Sotrage: | 4°C for 1 year, -20°C for more than 2 years |
Description: | Betulonic acid belongs to the pentacyclic triterpenic derivative class, has antitumor activities. |
In Vivo: | The animals are treated with betulonic acid amide (50 mg/kg in Tween aqueous solution) and heptral (6 mg/kg) as hepatoprotective compounds. It is found that betulonic acid amide stimulats the regenerative response in hepatocytes under conditions of combined toxic exposure and promots recovery of their qualitative and quantitative characteristics. [2] |
In Vitro: | BEA-NP is found over three-times more permeable than that solubilized by DMSO in Caco-2 cell monocultures.[1] |