Mepolizumab Datasheet DC Chemicals
Description Epratuzumab is a humanized monoclonal antibody derived from the murine IG2a monoclonal antibody, LL2 (EPB-2).
Cat.No A026
Name Mepolizumab

Chemical Properties

CAS 196078-29-2
Synonyms ImmunoglobulinG1, anti-(human interleukin 5) (human-mouse monoclonal SB-240563 g1-chain),disulfide with human-mouse monoclonal SB-240563 k-chain, dimer (9CI);(2S,3S,4S,5R,6R)-6-[[(4aR,6aR,6bS,8aS,14aR,14bR)-8a-carboxy-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,13,14,14a-tetradecahydropicen-3-yl]oxy]-3,5-dihydroxy-4-[(1R,2R,3S,4R)-2,3,4-trihyd;ImmunoglobulinG1, anti-(human interleukin 5) (human-mouse monoclonal SB-240563 g1-chain),disulfide with human-mouse monoclona;Bosatria;Sb 240563;mepolizumab;Immunoglobulin G1, anti-(human interleukin 5) (human-mouse monoclonal sb-240563 gamma1-chain), disulfide with human-mouse monoclonal sb-240563 kappa-chain, dimer;Mepolizumab
pH value Corresponds to reference standard: PASS
Non-reduced CE-SDS 98.3%
SEC-HPLC 99%
Isoelectric Point Corresponds to reference standard
Bacterial Endotoxins Test <1 EU/ml
Residual Proteins of Host Cell
Exogenous Residual DNA <1 pg/mg
Residual protein A <1 ng/mg
Biological Activity Compared with standard, the range ofbiological activity is 99%
Osmolality Corresponds to reference standard: PASS
Peptide mapping Corresponds to reference standard: PASS
N-terminal sequence Corresponds to reference standard:PASS

References

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