Description |
Epratuzumab is a humanized monoclonal antibody derived from the murine IG2a monoclonal antibody, LL2 (EPB-2). |
Cat.No |
A026 |
Name |
Mepolizumab |
Chemical Properties
CAS |
196078-29-2 |
|
Synonyms |
ImmunoglobulinG1, anti-(human interleukin 5) (human-mouse monoclonal SB-240563 g1-chain),disulfide with human-mouse monoclonal SB-240563 k-chain, dimer (9CI);(2S,3S,4S,5R,6R)-6-[[(4aR,6aR,6bS,8aS,14aR,14bR)-8a-carboxy-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,13,14,14a-tetradecahydropicen-3-yl]oxy]-3,5-dihydroxy-4-[(1R,2R,3S,4R)-2,3,4-trihyd;ImmunoglobulinG1, anti-(human interleukin 5) (human-mouse monoclonal SB-240563 g1-chain),disulfide with human-mouse monoclona;Bosatria;Sb 240563;mepolizumab;Immunoglobulin G1, anti-(human interleukin 5) (human-mouse monoclonal sb-240563 gamma1-chain), disulfide with human-mouse monoclonal sb-240563 kappa-chain, dimer;Mepolizumab |
pH value |
Corresponds to reference standard: PASS |
Non-reduced CE-SDS |
98.3% |
SEC-HPLC |
99% |
Isoelectric Point |
Corresponds to reference standard |
Bacterial Endotoxins Test |
<1 EU/ml |
Residual Proteins of Host Cell |
|
Exogenous Residual DNA |
<1 pg/mg |
Residual protein A |
<1 ng/mg |
Biological Activity |
Compared with standard, the range ofbiological activity is 99% |
Osmolality |
Corresponds to reference standard: PASS |
Peptide mapping |
Corresponds to reference standard: PASS |
N-terminal sequence |
Corresponds to reference standard:PASS |
References
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