NSC 146109 (hydrochloride) Datasheet DC Chemicals
Description NSC 146109 is an activator of the tumor suppressor p53 that increases expression of p53 and the p53 target DR5 in wild-type and p53-knockout HCT116 colon adenocarcinoma cells.
Cat.No DC11313
Name NSC 146109 (hydrochloride)

Chemical Properties

CAS 59474-01-0
Formula C17H16N2S.HCL
MW 316.8
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Wang H, et al. A small-molecule p53 activator induces apoptosis through inhibiting MDMX expression in breast cancer cells. Neoplasia. 2011 Jul;13(7):611-9.
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