A28-C6B2 Datasheet DC Chemicals

Description	A28-C6B2 is an ionizable lipid (pKa 6.43) designed for mRNA encapsulation in lipid nanoparticles (LNPs). Following intravenous injection in mice, these LNPs exhibit spleen-selective accumulation, particularly localizing in F4/80+ macrophages and CD11c+ dendritic cells, with moderate uptake by T lymphocytes.
Cat.No	DC67450
Name	A28-C6B2

Chemical Properties

CAS
Formula	C41H81NO5
MW	668.1
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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