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A28-C6B2

  Cat. No.:  DC67450  
Chemical Structure
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Field of application
A28-C6B2 is an ionizable lipid (pKa 6.43) designed for mRNA encapsulation in lipid nanoparticles (LNPs). Following intravenous injection in mice, these LNPs exhibit spleen-selective accumulation, particularly localizing in F4/80+ macrophages and CD11c+ dendritic cells, with moderate uptake by T lymphocytes.
Cas No.:
Chemical Name: A28-C6B2
SMILES: CCCCCCC(COC(CCCCCN(CCCCCC(OCC(CCCC)CCCCCC)=O)CCCCCO)=O)CCCC
Formula: C41H81NO5
M.Wt: 668.1
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Cat. No. Product name Field of application
DC67450 A28-C6B2 A28-C6B2 is an ionizable lipid (pKa 6.43) designed for mRNA encapsulation in lipid nanoparticles (LNPs). Following intravenous injection in mice, these LNPs exhibit spleen-selective accumulation, particularly localizing in F4/80+ macrophages and CD11c+ dendritic cells, with moderate uptake by T lymphocytes.
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