ALV2 Datasheet DC Chemicals
Description ALV2 is a potent and selective degrader of Helios, a zinc-finger transcription factor crucial for maintaining a stable regulatory T-cell (Treg) phenotype in inflammatory tumor microenvironments. ALV2 binds to CRBN with an IC50 of 0.57 μM, demonstrating its specificity and efficacy.
Cat.No DC47521
Name ALV2

Chemical Properties

CAS 2438124-95-7
Formula C26H26CLN5O5
MW 523.97
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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