bpV(phen) hydrate Datasheet DC Chemicals

Description	bpV(phen) hydrate is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor with IC50s of 38 nM, 343 nM and 920 nM for PTEN, PTP-β and PTP-1B, respectively. bpV(phen) hydrate inhibits proliferation of the protozoan parasite Leishmania in vitro. bpV(phen) hydrate strongly induces the secretion of a large number of chemokines and pro-inflammatory cytokines, and it activates a Th1-type pathway (IL-12, IFNγ). bpV(phen) hydrate can also induce cell apoptosis, and has anti-angiogenic and anti-tumor activity.
Cat.No	DC40790
Name	bpV(phen) hydrate

Chemical Properties

CAS
Formula	C12H8KN2O5V.XH2O
MW
Storage	Powder-20°C3 yearsIn solvent-80°C6 months-20°C1 month

References

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