bpV(phen) hydrate
Cat. No.: DC40790
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Field of application
bpV(phen) hydrate is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor with IC50s of 38 nM, 343 nM and 920 nM for PTEN, PTP-β and PTP-1B, respectively. bpV(phen) hydrate inhibits proliferation of the protozoan parasite Leishmania in vitro. bpV(phen) hydrate strongly induces the secretion of a large number of chemokines and pro-inflammatory cytokines, and it activates a Th1-type pathway (IL-12, IFNγ). bpV(phen) hydrate can also induce cell apoptosis, and has anti-angiogenic and anti-tumor activity.
Cas No.: |
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Chemical Name: |
bpV(phen) hydrate |
SMILES: |
O=[V+3]12([N]3=CC=C4)([O-][O-]1)([O-][O-]2)[N]5=C6C3=C4C=CC6=CC=C5.O.[x].[K+] |
Formula: |
C12H8KN2O5V.XH2O |
Sotrage: |
Powder-20°C3 yearsIn solvent-80°C6 months-20°C1 month |
MSDS
COA
LOT NO. |
DOWNLOAD |
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2018-0101 |
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