CPAG-1 Datasheet DC Chemicals

Description	CPAG-1 (PGRMC2 activator CPAG-1) is a small-molecule activator of PGRMC2. CPAG-1 treatment had no effect on weight or food intake but treated mice had reduced fasting glycemia and insulin levels. CPAG-1 decreased Rev-Erbα protein in BAT of CPAG-1-treated mice. CPAG-1 also significantly increased labile heme in the nucleus of brown adipocytes from CPAG-1-treated mice within 4 days of treatment.
Cat.No	DC73953
Name	CPAG-1

Chemical Properties

CAS	2094991-62-3
Formula	C20H26N2O2
MW	326.44
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

1. Andrea Galmozzi, et al. Nature. 2019 Dec;576(7785):138-142. 2. Christopher G Parker, et al. Cell. 2017 Jan 26;168(3):527-541.e29.

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