dCK1α-2 Datasheet DC Chemicals
Description dCK1α-2 is an orally bioavailable molecular glue degrader targeting CK1α, a key regulator of p53 pathway signaling. This compound demonstrates robust in vivo anti-tumor activity in murine models while upregulating expression of p53-associated genes, highlighting its dual mechanism of action.
Cat.No DC67364
Name dCK1α-2

Chemical Properties

CAS
Formula C24H23CLN6O4
MW 494.93
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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