MRTX849 ethoxypropanoic acid Datasheet DC Chemicals

Description	MRTX849 ethoxypropanoic acid incorporates a ligand for KRAS G12C, and a PROTAC linker. MRTX849 ethoxypropanoic acid can be used in the synthesis of PROTAC LC-2. LC-2 is a potent and first-in-class PROTAC capable of degrading endogenous KRAS G12C (DC50s between 0.25 and 0.76 μM).
Cat.No	DC46259
Name	MRTX849 ethoxypropanoic acid

Chemical Properties

CAS	2561529-98-2
Formula	C37H43CLFN7O5
MW	720.23
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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