S6821 Datasheet DC Chemicals

Description	S6821 (S 6821) is a potent and selective antagonist of the bitter taste receptor TAS2R8, exhibiting an IC50 value of 21 nM. It demonstrates high selectivity across a panel of 16 TAS2Rs, effectively reduces the bitterness of coffee, and shows an excellent safety profile.
Cat.No	DC73509
Name	S6821

Chemical Properties

CAS	1119831-25-2
Formula	C19H19N5O4
MW	381.392
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

Fotsing JR, et al. J Med Chem. 2020 May 14;63(9):4957-4977.

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