S6821
Cat. No.: DC73509
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Chemical Structure
1119831-25-2
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Field of application
S6821 (S 6821) is a potent and selective antagonist of the bitter taste receptor TAS2R8, exhibiting an IC50 value of 21 nM.
It demonstrates high selectivity across a panel of 16 TAS2Rs, effectively reduces the bitterness of coffee, and shows an excellent safety profile.
Cas No.: |
1119831-25-2 |
Chemical Name: |
S6821 |
Formula: |
C19H19N5O4 |
M.Wt: |
381.392 |
Purity: |
>98% |
Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Publication: |
Fotsing JR, et al. J Med Chem. 2020 May 14;63(9):4957-4977. |
Description: |
S6821 (S 6821) is a potent and selective antagonist of the bitter taste receptor TAS2R8, exhibiting an IC50 value of 21 nM.
It demonstrates high selectivity across a panel of 16 TAS2Rs, effectively reduces the bitterness of coffee, and shows an excellent safety profile. |
References: |
Fotsing JR, et al. J Med Chem. 2020 May 14;63(9):4957-4977. |
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