WDR5 inhibitor 41 Datasheet DC Chemicals

Description	WDR5 inhibitor 41 is a potent, selective and orally bioavailable WDR5 WIN-site inhibitor with TR-FRET Ki value of <0.02 nM, inhibits cell proliferation of MV4:11 and MOLM-13 with IC50 of 13 and 27 nM, respectively.WDR5 inhibitor 41 is well tolerated in mice by both iv and po dosing and showed no clinical sign of abnormalities suggesting an enhanced safetyprofile for the series.
Cat.No	DC70902
Name	WDR5 inhibitor 41

Chemical Properties

CAS	2417012-26-9
Formula	C29H29F3N6O
MW	534.587
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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