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COA of (Rac)-CFT7455
Description:
(Rac)-CFT7455 is a potent, racemic small-molecule degrader of the zinc finger transcription factors IKZF1 (Ikaros) and IKZF3 (Aiolos), operating through ubiquitin-proteasome-mediated degradation. It demonstrates exceptional cellular potency, with a GI50 of 0.05 nM in NCI-H929.1 cells. As the racemic form of CFT7455, it retains the same anticancer activity by selectively targeting IKZF1/3 for proteasomal destruction.
Chemical Information
| Catalog | Featured products |
|---|---|
| Purity of current batch | >98% |
| CAS | 2504233-68-3 |
| Molecular Weight (MW) | 469.53 |
| Molecular Formula | C28H27N3O4 |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Handling:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.