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(Rac)-CFT7455

  Cat. No.:  DC71590   Featured
Chemical Structure
2504233-68-3
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More than 5000 active chemicals with high quality for research!
Field of application
(Rac)-CFT7455 is a potent, racemic small-molecule degrader of the zinc finger transcription factors ​IKZF1 (Ikaros) and IKZF3 (Aiolos), operating through ​ubiquitin-proteasome-mediated degradation. It demonstrates exceptional cellular potency, with a ​GI50 of 0.05 nM in NCI-H929.1 cells. As the racemic form of ​CFT7455, it retains the same ​anticancer activity by selectively targeting IKZF1/3 for proteasomal destruction.
Cas No.: 2504233-68-3
Chemical Name: (Rac)-Cemsidomide
Synonyms: 2,6-Piperidinedione, 3-[6-[[4-(4-morpholinylmethyl)phenyl]methyl]-2-oxobenz[cd]indol-1(2H)-yl]-;(Rac)-Cemsidomide
SMILES: N1C(=O)CCC(N2C3=C4C(C=CC=C4C2=O)=C(CC2=CC=C(CN4CCOCC4)C=C2)C=C3)C1=O
Formula: C28H27N3O4
M.Wt: 469.53
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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