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COA of A12-Iso5-2DC18
Description:
A12-Iso5-2DC18 is a novel amine containing lipid can be used for mRNA delivery, activate the stimulator of interferon genes (STING) pathway, and exhibit anti-tumor immunity.
Chemical Information
| Catalog | Classic ionizable lipids for RNA delivery |
|---|---|
| Purity of current batch | >95% |
| CAS | 2412492-06-7 |
| Molecular Weight (MW) | 700.18 |
| Molecular Formula | C45H85N3O2 |
Handling:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Reference:
Synthesis of ionizable lipidoids for pharmaceutical use
By: Miao, Lei; Li, Linxian; Anderson, Daniel Griffith; Huang, Yuxuan
World Intellectual Property Organization, WO2020047399 A1 2020-03-05.