KSQ-4279 (Synonyms: USP1-IN-1) Datasheet DC Chemicals

Description	KSQ-4279 is a USP1 and PARP inhibitor. KSQ-4279 showed anti-proliferative effects in a subset of cell lines, often characterized by the presence of homologous recombination deficiencies (HRD), including mutations in BRCA1/2. The combination of KSQ-4279 with olaparib was able to induce strong and durable regressions across a number of ovarian and TNBC PDX models.
Cat.No	DC60562
Name	KSQ-4279 (Synonyms: USP1-IN-1)

Chemical Properties

CAS	2446480-97-1
Formula	C27H25F3N8O
MW	534.54
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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