6-Diazo-5-oxo-L-nor-Leucine Datasheet DC Chemicals

Description	6-Diazo-5-oxo-L-nor-Leucine (DON) is a glutamine analog that inhibits glutaminases (Ki = 6 µM) and other glutamine-utilizing enzymes, including cytidine triphosphate synthase (CTPS), which uses glutamine in the synthesis of CTP.1,2,3 DON is commonly used in cells or tissues but its use in whole animals is limited by its teratogenicity.
Cat.No	DC60563
Name	6-Diazo-5-oxo-L-nor-Leucine

Chemical Properties

CAS	157-03-9
Formula	C6H9N3O3
MW	171.15396
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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