NMDAR/TRPM4-IN-2 Datasheet DC Chemicals

Description	NMDAR/TRPM4-IN-2 (compound 8) is a potent NMDAR/TRPM4 interaction interface inhibitor. NMDAR/TRPM4-IN-2 shows neuroprotective activity. NMDAR/TRPM4-IN-2 prevents NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons, with an IC50 of 2.1 μM. NMDAR/TRPM4-IN-2 protects mice from MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss.
Cat.No	DC66079
Name	NMDAR/TRPM4-IN-2

Chemical Properties

CAS	2243506-33-2
Formula	C11H18BRCLN2
MW	293.631021022797
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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