E3 Ligase Ligand-Linker Conjugates 22|cas 2225940-52-1|DC Chemicals

Cas No.:	2225940-52-1
Chemical Name:	E3 Ligase Ligand-Linker Conjugates 22
Synonyms:	Pomalidomide-PEG4-C2-NH2;BCP33438;4-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethylamino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;E3 Ligase Ligand-Linker Conjugates 22
SMILES:	O=C1C([H])(C([H])([H])C([H])([H])C(N1[H])=O)N1C(C2C([H])=C([H])C([H])=C(C=2C1=O)N([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])[H])=O
Formula:	C₂₃H₃₂N₄O₈
M.Wt:	492.5222
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

E3 Ligase Ligand-Linker Conjugates 22 incorporates an E3 ligase ligand and a linker, can be used for the treatment of EZH2-mediated cancer.

Cat. No.	Product name	Field of application
DC39625	(S,R,S)-AHPC-PEG4-NH2 hydrochloride	VH 032 Linker 2 is a derivative of the proteolysis-targeting chimera technology (PROTAC) building block VHL ligand 1.
DC50079	Thalidomide-O-amido-C5-NH2	Thalidomide-O-amido-C5-NH2 is a novel PROTAC building block.
DC50078	(S,R,S)-AHPC-Me-C8-NH2	(S,R,S)-AHPC-Me-C8-NH2 is a novel PROTAC building block.
DC50077	(S,R,S)-AHPC-Me-C4-NH2	(S,R,S)-AHPC-Me-C4-NH2 is a novel PROTACA building block.
DC50076	(S,R,S)-AHPC-Me-C3-NH2	(S,R,S)-AHPC-Me-C3-NH2 is a novel PROTAC building block.
DC50075	(S,R,S)-AHPC-Me-C2-NH2	(S,R,S)-AHPC-Me-C2-NH2 is a novel PROTAC building block.
DC50074	(S,R,S)-AHPC-Me-C1-NH2	(S,R,S)-AHPC-Me-C1-NH2 is a novel PROTAC Building block.
DC50070	(S,R,S)-AHPC-PEG2-NH2 (E3 ligase Ligand-Linker Conjugates 6 Free Base)	(S,R,S)-AHPC-PEG2-NH2 (VH032-PEG2-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs.
DC50069	(S,R,S)-AHPC-PEG4-NH2(E3 ligase Ligand-Linker Conjugates 7)	(S,R,S)-AHPC-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.
DC50068	(S,R,S)-AHPC-Me-C10-NH2	(S,R,S)-AHPC-Me-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C10-NH2 can be used in PROTAC MS432