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Home > Inhibitors & Agonists > Metabolic Enzyme/Protease > Drug Metabolite

Drug Metabolite

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Cat. No. Product Name Field of Application Chemical Structure
DC81817 ΔDi6S sodium
ΔDi6S sodium is a chondroitin that can be isolated from chondroitin-4-sulfate in whale cartilage.
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DC81803 αGlcCer
αGlcCer is a glycosphingolipid.
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DC81796 ZX-2401
ZX-2401 (Compound 98a) is a 1,3,5-Triazine-based analogue of Purine. ZX-2401 has a significant antiviral activity against viruses of the Flaviviridae family, such as West Nile Virus (WNV), Hepatitis C (HCV), Yellow Fever Virus (YFV), Dengue Virus (DV), Bovine Viral Diarrhea Virus (BVDV) and Banzi Virus (BV) with EC90s of 0.6-10 μg/mL. ZX-2401 significantly reduces virus production with an EC90 of 3.3 mg/mL. ZX-2401 can be used for influenza infections research.
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DC81555 SNA C(Bz) amidite
SNA C(Bz) amidite is a phosphoramide monomer that can be used to synthesize oligonucleotides.
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DC81506 SCH 47896
SCH 47896 is a phenolic derivative of SCH39370, a potent specific inhibitor of metalloendopeptidase (NEP). SCH 47896 can be used for the research of cardiovascular disease, such as hypertension.
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DC81427 Quindoxin
Quindoxin is an antibacterial and growth promoter, commonly used in the livestock industry. Quindoxin exhibits clear dose-dependent mutagenic activity against Salmonella typhimurium TA98 and TA100 strains. Quindoxin can cause DNA damage and has potential genotoxicity and carcinogenic risks.
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DC81422 PZ-1129
PZ-1129 is a selective 5-HT7 receptor ligand with a Ki of 7 nM. PZ-1129 shows Ki values of 159 and 24 nM for 5-HT1A receptor and D2 receptor. PZ-1129 can inhibit the constitutive cAMP production mediated by the Gs signaling pathway (EC50 = 13.7 nM). PZ-1129 can be used for the research of emotional disorders, such as depression and bipolar disorder.
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DC81296 Piroctone
Piroctone is a potent hydroxypyridone antimicrobial agent that shows remarkable activity against fungi including Candida species. Piroctone inhibits hyphal induction of Candida albicans. Piroctone can efficiently chelate intracellular iron to induce relevant cytotoxicity in neuroblastoma cells. Piroctone can be used for antimicrobial and neuroblastoma research.
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DC81178 NSC 660028
NSC 660028 is a DNA topoisomerase II (DNA topoisomerase II) inhibitor with an ID50 of 50 μM. NSC 660028 inhibits DNA topoisomerase II and induces protein-linked DNA breaks. NSC 660028 can be used for cancer research.
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DC81104 N,N-Dimethyl psychosine
N,N-Dimethyl psychosine is a derivative of Psychosine. N,N-Dimethyl psychosine can be used as an internal standard compound to quantify Psychosine in alkaline-treated lipid extracts.
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DC80944 LC-61
LC-61 is a potent antileishmanial agent with an IC50 of 0.076 µM against intracellular L. infantum.
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DC80850 Imidazole-4-pyruvic acid
Imidazole-4-pyruvic acid is derived from histidine catalyzed by histidine transaminase. Imidazole-4-pyruvic acid can be used as a precursor for selective His-labeling in E.coli overexpressed proteins.
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DC80666 Flumezapine
Flumezapine (LY 120363) is a potent and balanced antagonist of the dopamine D2 receptor and the 5-hydroxytryptamine receptor (5-HT receptor). Flumezapine does not alter the increase in serum cortisol caused by κ-opioid receptor agonists. Flumezapine inhibits the conditioned avoidance response in rats and has a low risk of extrapyramidal side effects. Flumezapine can be used in antipsychotic research.
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DC80633 F-15845 hydrobromide
F 15845 hydrobromide is a highly effective persistent sodium current blocker. F 15845 hydrobromide is also a cardioprotective agent, has anti-ischemic activity and exerts short- and long-term cardioprotection after myocardial infarction. F 15845 hydrobromide can be used for the research of myocardium functional impairment.
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DC80628 Ethyl biscoumacetate
Ethyl biscoumacetate is an anticoagulant and vitamin K antagonist. Ethyl biscoumacetate can be used in the research of experimental venous thrombosis.
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DC80503 D-473
D-473 is an orally active, blood-brain barrier penetrant and serotonin-preferring reuptake inhibitor. D-473 inhibits serotonin, dopamine and norepinephrine transporters, and significantly elevates the extracellular levels of these three neurotransmitters in rat brain regions. D-473 exhibits definite antidepressant-like activity without inducing motor activation. D-473 is widely used in studies related to major depressive disorder.
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DC80456 Clethodim sulfone
Clethodim sulfone is a clethodim oxidation metabolite. Clethodim is one of the most widely used herbicides in agriculture
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DC80294 BAY-Y 3118 hydrochloride
BAY-Y 3118 hydrochloride is a quinolone antibacterial agent. BAY-Y 3118 hydrochloride has a broad antibacterial spectrum in vitro. BAY-Y 3118 hydrochloride exhibits high activity against gram-positive cocci and anaerobes. BAY-Y 3118 hydrochloride shows moderate activity against Enterobacteriaceae and Pseudomonas aeruginosa. BAY-Y 3118 hydrochloride can be used in the research of infectious diseases.
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DC80201 Anordrin
Anordrin is a contraceptive agent. Anordrin exhibits estrogenicites and can induce decrease in serum progesterone levels in rat models. Anordrin inhibits endometrial epithelial cell mitosis and NAFLD induced by Tamoxifen in mouse uterus and liver as an anti-estrogenic and estrogenic agent.
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DC80131 9,10-Epoxy13-hydroxy-11-octadecenoic acid
9,10-Epoxy13-hydroxy-11-octadecenoic acid is a fatty acid.
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DC80097 5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole is a nucleoside metabolite.
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DC79875 (±)-Homoproline
(±)-Homoproline (2-Pyrrolidineacetic acid) is the precursor for the biosynthesis of Tussilagine and Isotussilagine. (±)-Homoproline can be used in neurological research.
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DC76898 Piribedil N-oxide
Piribedil N-oxide is a metabolite of the dopamine receptor agonist Piribedil.
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DC76897 N-Desmethyl rosiglitazone
N-Desmethyl rosiglitazone (SB 237216) is a metabolite of Rosiglitazone, generated through demethylation by the cytochrome P450 enzyme system in liver microsomes. It retains partial PPARγ agonist activity and supports studies on the metabolism and pharmacokinetics of Rosiglitazone.
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DC76896 Desmethyl mirtazapine hydrochloride
Desmethyl mirtazapine (Normirtazapine) hydrochloride is a metabolite of Mirtazapine. Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent.
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DC76895 10-Hydroxywarfarin
10-Hydroxywarfarin, a metabolite of (R)-(+)-Warfarin, is a CYP2C9 and vitamin K epoxide reductase complex 1 (VKOR) inhibitor with IC50s of 1.6 µM and 80 ng/mL, respectively.
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DC71390 Ribavirin carboxylic acid Featured
Ribavirin carboxylic acid (TR-COOH) is a metabolite of ribavirin, ribavirin has strong antiviral activity.
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DC29031 Enzalutamide carboxylic acid Featured
Enzalutamide carboxylic acid (MDV3100 carboxylic acid) is an inactive metabolite of Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist.
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DC28845 N-Desmethyl Pimavanserin Featured
N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin. Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC50 and pKd of 8.73 and 9.3, respectively.
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DC72846 S-Allylmercapturic acid
S-Allylmercapturic acid is a biomarker of food intake (BFIs) for garlic consumption.
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