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Home > Inhibitors & Agonists > Metabolic Enzyme/Protease > COMT

COMT

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Cat. No. Product Name Field of Application Chemical Structure
DC76848 Methylspinazarin
Methylspinazarin is a potent inhibitor of catechol O-methyltransferase (COMT, IC50 = 0.8 μg/ml) that can be isolated from Streptomyces. Methylspinazarin is selective for COMT over tyrosine hydroxylase.
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DC11485 Tolcapone Featured
Tolcapone is an orally active catechol-O-methyltransferase (COMT) inhibitor.
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DC40579 5-Hydroxyferulic acid
5-Hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrate.
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DC28087 3-O-Methyltolcapone
3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone. Tolcapone is an orally active, reversible, selective and potent COMT inhibitor. Tolcapone crosses the blood-brain barrier, and can be used for treatment of Parkinson's disease.
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DC11094 Neluxicapone

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