2,4,5-T|CAS 93-76-5|DC Chemicals

Cas No.:	93-76-5
Chemical Name:	2,4,5-T Standard
Synonyms:	2-(2,4,5-Trichlorophenoxy)acetic acid;2,4,5-T;(2,4,5-Trichloor-fenoxy)-azijnzuur;(2,4,5-trichloor-fenoxy)-azijnzuur[qr];(2,4,5-trichlorophenoxy)-aceticaci;(2,4,5-trichlorophenoxy)ethanoicacid;(2,4,5-Trichlor-phenoxy)-essigsaeure;(2,4,5-trichlor-phenoxy)-essigsaeure[qr];,4,5-Trichlorophenoxyacetic acid;2,4,5-Trichlorophenoxyacetica;2,4,5-T solution;2,4,5-trichlorophenoxy-acetic acid;arbokan;Forron;Fortex;Phortox;Reddon;Reddox;Tippon;Trioxon;VEON;TIMTEC-BB SBB003114;WEEDONE;'LGC' (1310);2,4,5-T (TM);2,4,5-TRICHLOROPHENOXYACETIC ACID;2,4,5-T ACID;2,4,5-trichlorophenoxyacetic;2,4,5-T Standard;2,4,5-Trichlorophenoxyacetic acid solution
SMILES:	C(O)(=O)COC1=CC(Cl)=C(Cl)C=C1Cl
Formula:	C₈H₅Cl₃O₃
M.Wt:	255.48
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
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DC79856	EVT0185	EVT0185 is an orally active ATP citrate lyase (ACLY) inhibitor. EVT0185 is converted to a CoA thioester in the liver by SLC27A2 and interacts with the CoA-binding site of ACLY. EVT0185-CoA inhibits ACLY activity with an IC50 of 2.5 μM. EVT0185 can phenocopy the immune and antitumour effects of genetic ACLY deletion. EVT0185 can increase tumour-infiltrating B cells and chemokine CXCL13 levels. EVT0185 can be used for the research of cancer, such as hepatocellular carcinoma (HCC).
DC79609	NCGC00685960	NCGC00685960 is a Nicotinamide N-methyltransferase (NNMT) inhibitor with an IC50 < 10  nM. NCGC00685960 has potent antitumor activity. NCGC00685960 increases H3K27 trimethylation levels in ovarian cancer cells and inhibits α-SMA expression in NNMT-expressing ovarian fibroblasts. NCGC00685960 reduces 1-MNA levels, reverses SAM and H3K27 hypomethylation and significantly impairs collagen contractility in cancer-associated fibroblasts (CAFs). NCGC00685960 can be used for cancers research.
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DC79112	Simepdekinra	Simepdekinra (Compound 221) is a IL-17A modulator with IC50s ≤10  nM and 10-100 nM for IL-17A/A HEK-Blue and IL-17A/F HEK-Blue cells. Simepdekinra can be used for inflammatory diseases such as psoriasis, ankylosing spondylitis and psoriatic arthritis research.
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DC78592	ZINC13000658	ZINC13000658 is a METTL inhibitor. ZINC13000658 exhibits significant anti proliferative activity in various cells and can induce G1 phase cell cycle arrest and apoptosis such as HepG2 (IC50 = 5.632 µM) and SNU-449 (IC50 = 6.184 µM) cells. ZINC13000658 may be related to the inhibition of the activity of multiple methyltransferases such as METTL1, 3, 6, 16, 18, etc. ZINC13000658 can be used for research on various types of cancer.
DC78326	XL-3156	XL-3156 is a potent, selective, and cross-species cGAS inhibitor. XL-3156 can simultaneously occupy both allosteric and orthosteric sites, and inhibit the interaction and phase separation between cGAS and DNA by stabilizing the closed conformation of the activation loop. XL-3156 can be used in the research of autoimmune diseases, inflammatory conditions and other diseases.
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2,4,5-T Standard